Alex Rolband

Prior to joining the firm, Alex briefly worked as a postdoctoral research scholar at North Carolina State University after receiving his Ph.D. in Nanoscale Science from the University of North Carolina at Charlotte. His research background as a biophysical chemist focused heavily on the design and characterization of therapeutic nucleic acids for applications as gene therapies, antibiotics, and anticoagulants. Alex also served 8 years in the North Carolina Army National Guard as an artillery observer.

• Member, American Chemical Society, 2016-Present

• Speaker, “Investigating the mechanism of Nsa1 removal from the pre-60s ribosomal subunit by Rix7 through single-molecule FRET,” SERMACS 2023, October 2023.
• Speaker, “Assessing the Biological Activities of DNA-Templated Silver Nanoclusters,” Complex Matter and Biophysics Seminar, September 2023.
• Speaker, “SAXS for NANPs: Advancing the Structural Characterization of Ribonucleic Acid Nanoparticles Through Small-Angle X-ray Scattering,” ASBMB 2023, March 2023.
• Speaker, “Enhanced Structural Characterization of Multi-stranded Nucleic Acid Nanoparticles,” SERMACS 2021, November 2021.
• Speaker, “Using RNA Nanoring Scaffolds to Modulate the Fluorescent Properties of Silver Nanoclusters, 22nd Rustbelt RNA Meeting, October 2020.
• Speaker, “Recent Uses of SAXS in Probing Nucleic Acid Nanotechnology Structure and Function,” Smart Materials Programmed to Operate in Living Systems, May 2020.

• Co-Author, “Demonstrating the Synthesis and Antibacterial Properties of Nanostructured Silver,” Journal of Chemical Education, 2023.
• Co-Author, “Optical, structural and antibacterial properties of silver nanoparticles and DNA-templated silver nanoclusters,” Nanomedicine, 2023.
• Co-Author, “Expanding Structural Space for Immunomodulatory Nucleic Acid Nanoparticles via Spatial Arrangement of Their Therapeutic Moieties,” Advanced Functional Materials, 2022.
• Co-Author, “Locking and Unlocking Thrombin Function Using Immunoquiescent Nucleic Acid Nanoparticles with Regulated Retention In Vivo,” Nano Letters, 2022.
• Co-Author, “Biomotors, viral assembly, and RNA nanobiotechnology: Current achievements and future directions,” Computational and Structural Biotechnology Journal, 2022.
• Co-Author, “DNA-Templated Fluorescent Silver Nanoclusters Inhibit Bacterial Growth While Being Non-Toxic to Mammalian Cells,” Molecules, 2021.
• Co-Author, “Challenges to optimizing RNA nanostructures for large scale production and controlled therapeutic properties,” Nanomedicine, Future Medicine, 2020.
• Co-Author, “Tuning properties of silver nanoclusters with RNA nanoring assemblies,” Nanoscale, 2020.
• Co-Author, “Small-Angle Scattering as a Structural Probe for Nucleic Acid Nanoparticles (NANPs) in a Dynamic Solution Environment,” Nanomaterials, MDPI, 2019.
• Co-Author, “The Natural Versatility of RNA,” RNA Nanotechnology and Therapeutics, 2022.
• Co-Author, “Light Scattering Techniques for Characterization of NANPs and Their Formulations,” RNA Nanotechnology and Therapeutics, 2022.
• Co-Author, “Anticoagulant Activity of Nucleic Acid Nanoparticles (NANPs) Assessed by Thrombin Generation Dynamics on a Fully Automated System,” Methods in Molecular Biology, 2023.
• Co-Author, “Synthesis of DNA-Templated Silver Nanoclusters and the Characterization of Their Optical Properties and Biological Activity,” Methods in Molecular Biology, 2023.
• Co-Author, “Aptamer Conjugated RNA/DNA Hybrid Nanostructures Designed for Efficient Regulation of Blood Coagulation,” Methods in Molecular Biology, 2023.
• Co-Author, “Structural Characterization of Nucleic Acid Nanoparticles Using SAXS and SAXS-Driven MD,” Methods in Molecular Biology, 2023.